Retrovirus production protocols – Frontiers of Retrovirology

Retroelement Insertion in a CRISPR/Cas9 Editing Site in the Early Embryo Intensifies Genetic Mosaicism. Retrovirus production protocols Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing.

Deficiency of two-pore segment channel 2 contributes to systemic lupus erythematosus via regulation of apoptosis and cell cycle

Systemic lupus erythematosus (SLE) is a complex autoimmune disease, and the mechanism of SLE is yet to be fully elucidated.

Transduction of oncogenes by retroviruses

Transduction of oncogenes by retroviruses: what are the stages and mechanisms ?

July 17, 2020July 17, 2020 Christine 0 Comments

Transduction is the process by which a retrovirus captures a cellular gene. Repeated passages of an oncogene-free retrovirus on quiescent cultures

RETROVIRAL & LENTIVIRAL VECTOR APPLICATIONS Retrovirus production protocols

RETROVIRAL & LENTIVIRAL VECTOR APPLICATIONS

June 28, 2020June 28, 2020 Christine 0 Comments

Lentiviral vectors have been used successfully to transduce various cell types, such as neurons, hepatocytes, haematopoietic stem cells, retinal cells,

Retrovirus production protocols

Retrovirus & Lentivirus: what is the best protocol to produce and purify them?

June 25, 2020June 25, 2020 Christine 0 Comments

Lentiviral (LV) vectors offer unique advantages over other gene delivery systems, namely the ability to integrate transgenes into the genome