Frontiers of Retrovirology – Complex retroviruses, retroelements, HIV p24 and their hosts

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Discovery and characterization of the evolution, variation and functions of diversity-generating retroelements using thousands of genomes and metagenomes. Retroelement Insertion in a CRISPR/Cas9 Editing Site in the Early Embryo Intensifies Genetic Mosaicism.

Selective Display of a Chemoattractant Agonist on Cancer Cells Activates the Formyl Peptide Receptor 1 on Immune Cells

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Current immunotherapeutics typically work by directing elements of the immune system to acknowledge biomarkers on the floor of most cancers

Discovery and characterization of the evolution, variation and functions of diversity-generating retroelements using thousands of genomes and metagenomes. Retroelement Insertion in a CRISPR/Cas9 Editing Site in the Early Embryo Intensifies Genetic Mosaicism.

Performance Evaluation of the PowerChek SARS-CoV-2, Influenza A & B Multiplex Real-Time PCR Kit in Comparison with the BioFire Respiratory Panel

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Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and influenza viruses could pose huge challenges to our healthcare system. We evaluated the

Discovery and characterization of the evolution, variation and functions of diversity-generating retroelements using thousands of genomes and metagenomes. Retroelement Insertion in a CRISPR/Cas9 Editing Site in the Early Embryo Intensifies Genetic Mosaicism.

Emergency SARS-CoV-2 Variants of Concern: Novel Multiplex Real-Time RT-PCR Assay for Rapid Detection and Surveillance

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Coronavirus illness 2019 (COVID-19), attributable to extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has unfold worldwide. Many variants of SARS-CoV-2

Retroelement Insertion in a CRISPR/Cas9 Editing Site in the Early Embryo Intensifies Genetic Mosaicism. Retrovirus production protocols Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing.

Deficiency of two-pore segment channel 2 contributes to systemic lupus erythematosus via regulation of apoptosis and cell cycle

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Systemic lupus erythematosus (SLE) is a complex autoimmune disease, and the mechanism of SLE is yet to be fully elucidated.

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Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF), is a potent mediator of angiogenesis and vasculogenesis

Transduction of oncogenes by retroviruses

Transduction of oncogenes by retroviruses: what are the stages and mechanisms ?

July 17, 2020July 17, 2020 Christine 0 Comments

Transduction is the process by which a retrovirus captures a cellular gene. Repeated passages of an oncogene-free retrovirus on quiescent cultures

RETROVIRAL & LENTIVIRAL VECTOR APPLICATIONS Retrovirus production protocols

RETROVIRAL & LENTIVIRAL VECTOR APPLICATIONS

June 28, 2020June 28, 2020 Christine 0 Comments

Lentiviral vectors have been used successfully to transduce various cell types, such as neurons, hepatocytes, haematopoietic stem cells, retinal cells,

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