Retroelement Insertion in a CRISPR/Cas9 Editing Site in the Early Embryo Intensifies Genetic Mosaicism.

Continued CRISPR/Cas9-mediated enhancing exercise that enables differential and asynchronous modification of alleles in successive cell generations expands allelic complexity. To perceive the earliest occasions throughout CRISPR/Cas9 enhancing and the allelic choice amongst the progeny of subsequent cell divisions, we inspected in element the genotypes of 4- and 8-cell embryos and embryonic stem cells (ESCs) after microinjection of a CRISPR toolkit into the zygotes.

We discovered a increased enhancing frequency in 8-cell embryos than in 4-cell embryos, indicating that the CRISPR/Cas9 exercise endured by the 8-cell stage. Analysis of a CRISPR/Cas9 transgenic founder mouse revealed that 4 totally different alleles had been current in its organs in totally different mixtures and that its germline included three totally different mutant alleles, as proven by the genotypes of the pups.

The indel depth, which measured the extent of indels at the sequence degree inside single embryos, decreased considerably as the embryos superior to type ESCs, suggesting that exclusion of deadly indels occurred in the subsequent cell generations. Interestingly, we found that the CRISPR websites continuously contained launched retroelement sequences and that this occurred preferentially with sure lessons of retroelements.

Therefore, in addition to CRISPR/Cas9’s innate mechanism of separate, differential enzymatic modifications of alleles, the frequent retroelement insertions that happen in early mouse embryos throughout CRISPR/Cas9 enhancing additional broaden the allelic variety and mosaicism in the ensuing transgenic founders.

Retroelement Insertion in a CRISPR/Cas9 Editing Site in the Early Embryo Intensifies Genetic Mosaicism.
Retroelement Insertion in a CRISPR/Cas9 Editing Site in the Early Embryo Intensifies Genetic Mosaicism.

DiD perchlorate

T15118-1g 1g Ask for price
Description: DiD perchlorate

DiD perchlorate

T15118-1mg 1mg Ask for price
Description: DiD perchlorate

DiD perchlorate

T15118-50mg 50mg Ask for price
Description: DiD perchlorate

DiD perchlorate

T15118-5mg 5mg Ask for price
Description: DiD perchlorate

DiD perchloRate

MBS8579557-10mg 10mg
EUR 190

DiD perchloRate

MBS8579557-5x10mg 5x10mg
EUR 710

DiD perchlorate

MBS3841916-100mg 100mg
EUR 1185

DiD perchlorate

MBS3841916-10mg 10mg
EUR 230

DiD perchlorate

MBS3841916-50mg 50mg
EUR 655

DiD perchlorate

MBS3841916-5mg 5mg
EUR 165

DiD perchlorate

MBS3841916-5x100mg 5x100mg
EUR 5330

DiD perchlorate

MBS5754787-10mg 10mg
EUR 200

DiD perchlorate

MBS5754787-1mg 1mg
EUR 145

DiD perchlorate

MBS5754787-25mg 25mg
EUR 280

DiD perchlorate

MBS5754787-50mg 50mg
EUR 380

DiD perchlorate

MBS5754787-5mg 5mg
EUR 175

DiD (DiIC18(5))

BMD0073-10mg 10 mg
EUR 59
Description: The far-red fluorescent, lipophilic carbocyanine DiD is a longer-wavelength DiI analog.

DiD (DiIC18(5))

BMD0073-each each Ask for price

DiD (DiIC18(5))

BMD0073-Null Null Ask for price

DiD (DiIC18(5))

MBS9719182-10mg 10mg
EUR 115

DiD (DiIC18(5))

MBS9719182-5x10mg 5x10mg
EUR 470

The Tweezer Repair Kit; allows you to straighten, resharpen, and repair your tweezers that have been damaged or have become dull. includes: 1 Sharpening stone Ten O-rings Instrument Oil, 50 ml Chain nose pliers Instructions

M-CEM-72892-10 -
EUR 176
Description: The Tweezer Repair Kit; allows you to straighten, resharpen, and repair your tweezers that have been damaged or have become dull. includes: 1 Sharpening stone Ten O-rings Instrument Oil, 50 ml Chain nose pliers Instructions

DID (DIIC18(5)), 5x1mg

60014-5mg 5MG
EUR 130
Description: N/A

DID (DIIC18(5)), 5x1mg

60014-5mg-1 EA
EUR 130

DiD Cell Labeling Solution

EGY029 1mL
EUR 120

DiD Cell Labeling Solution

MBS8579558-1mL 1mL
EUR 210

DiD Cell Labeling Solution

MBS8579558-5x1mL 5x1mL
EUR 800

DiD Perchlorate *UltraPure Grade*

22034-25mg 25 mg
EUR 86
Description: DiI, DiO, DiD and DiR dyes are a family of lipophilic fluorescent stains for labeling membranes and other hydrophobic structures.

Multiple Tumor Tissue Array - 15 major types tumors. Most types have duplicates from different patients with correspondi

Z7020081 5 slides
EUR 1125.6
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Multiple Tumor Tissue Array - 40 types of tumors. Most of them have duplicates or triplicates from different individual

Z7020082 5 slides
EUR 1657.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

DID (DIIC18(5)), 10 mg

60014-10mg 1MG
EUR 206
Description: N/A

DID (DIIC18(5)), 10 mg

60014-10mg-1 EA
EUR 206

Rat Deiodinase (DID) ELISA Kit

MBS3808344-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat Deiodinase (DID) ELISA Kit

MBS3808344-48StripWells 48-Strip-Wells
EUR 550

Rat Deiodinase (DID) ELISA Kit

MBS3808344-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat Deiodinase (DID) ELISA Kit

MBS3808344-96StripWells 96-Strip-Wells
EUR 765

HPV

MBS370080-INQUIRE INQUIRE Ask for price

OKEH02470-96W - DID ELISA Kit (Rat)

OKEH02470-96W 96Wells
EUR 625

HPV-16 E6 + HPV-18 E6 Antibody

V8334-100UG 100 ug
EUR 424.15
Description: Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis has shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.

HPV-16 E6 + HPV-18 E6 Antibody

V8334-20UG 20 ug
EUR 186.15
Description: Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis has shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.

HPV-16 E6 + HPV-18 E6 Antibody

V8334SAF-100UG 100 ug
EUR 424.15
Description: Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis has shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.

OKEH00588-96W - DID ELISA Kit (Mouse)

OKEH00588-96W 96Wells
EUR 625

Rabbit Anti Human KDM1A Monoclonal Clone DID-11

IRBAHUKDM1ADID11C100UL each
EUR 496
Description: Rabbit Anti Human KDM1A Monoclonal Clone DID-11

HPV-16 E6 Monoclonal antibody [Clone: HPV-13E2]

HPV-13E2-100ug 100 ug
EUR 141.79
Description: Identification of HPV-16 E6.

HPV-16 E6 Monoclonal antibody [Clone: HPV-13E2]

HPV-13E2-1mg 1 mg
EUR 897.6
Description: Identification of HPV-16 E6.

HPV-16 E6 Monoclonal antibody [Clone: HPV-13E2]

HPV-13E2-500ug 500 ug
EUR 479.6
Description: Identification of HPV-16 E6.

HPV-18 E6 Monoclonal antibody [Clone: HPV-4G3]

HPV-4G3-100ug 100 ug
EUR 141.79
Description: Identification of HPV-18 E6.

HPV-18 E6 Monoclonal antibody [Clone: HPV-4G3]

HPV-4G3-1mg 1 mg
EUR 897.6
Description: Identification of HPV-18 E6.

HPV-18 E6 Monoclonal antibody [Clone: HPV-4G3]

HPV-4G3-500ug 500 ug
EUR 479.6
Description: Identification of HPV-18 E6.

HPV-16 E6 Monoclonal antibody [Clone: HPV-4B12]

HPV-4B12-100ug 100 ug
EUR 141.79
Description: Identification of HPV-16 E6.

HPV-16 E6 Monoclonal antibody [Clone: HPV-4B12]

HPV-4B12-1mg 1 mg
EUR 897.6
Description: Identification of HPV-16 E6.

HPV-16 E6 Monoclonal antibody [Clone: HPV-4B12]

HPV-4B12-500ug 500 ug
EUR 479.6
Description: Identification of HPV-16 E6.

DID ELISA Kit (Rat) : 96 Wells (OKEH02470)

OKEH02470 96 Wells
EUR 934.8
Description: Description of target: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. A similar protein in human, mouse, and pig has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, the protein can function as a protease.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Competitive ELISA;Sensitivity: 0.47 ng/mL

DID ELISA Kit (Mouse) : 96 Wells (OKEH00588)

OKEH00588 96 Wells
EUR 934.8
Description: Description of target: ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.46 ng/mL

HPV-16 Antibody

abx021894-1mg 1 mg
EUR 1011.6

HPV-16 Antibody

abx021895-1mg 1 mg
EUR 961.2

Recombinant HPV HPV 11 Protein, GST, E.coli-1mg

QP12306-1mg 1mg
EUR 1513.2

Recombinant HPV HPV 16 Protein, GST, E.coli-1mg

QP12307-1mg 1mg
EUR 1513.2

Recombinant HPV HPV 18 Protein, GST, E.coli-1mg

QP12308-1mg 1mg
EUR 1513.2

Recombinant HPV HPV 6 Protein, GST, E.coli-1mg

QP12309-1mg 1mg
EUR 1513.2

Recombinant HPV HPV 11 Protein, GST, E.coli-100ug

QP12306-100ug 100ug
EUR 261.6

Recombinant HPV HPV 11 Protein, GST, E.coli-500ug

QP12306-500ug 500ug
EUR 795.6

Recombinant HPV HPV 16 Protein, GST, E.coli-100ug

QP12307-100ug 100ug
EUR 261.6

Recombinant HPV HPV 16 Protein, GST, E.coli-500ug

QP12307-500ug 500ug
EUR 795.6

Recombinant HPV HPV 18 Protein, GST, E.coli-100ug

QP12308-100ug 100ug
EUR 261.6

Recombinant HPV HPV 18 Protein, GST, E.coli-500ug

QP12308-500ug 500ug
EUR 795.6

Recombinant HPV HPV 6 Protein, GST, E.coli-100ug

QP12309-100ug 100ug
EUR 261.6

Recombinant HPV HPV 6 Protein, GST, E.coli-500ug

QP12309-500ug 500ug
EUR 795.6

HPV-16 E6 + HPV-18 E6 (Human Papilloma Virus 16/18)

MBS4381516-002mgWithBSAAzideat02mgmL 0.02mg(WithBSA&Azideat0.2mg/mL)
EUR 230

HPV-16 E6 + HPV-18 E6 (Human Papilloma Virus 16/18)

MBS4381516-01mgWithBSAAzideat02mgmL 0.1mg(WithBSA&Azideat0.2mg/mL)
EUR 405

HPV-16 E6 + HPV-18 E6 (Human Papilloma Virus 16/18)

MBS4381516-01mgWithoutBSAAzideat1mgmL 0.1mg(WithoutBSA&Azideat1mg/mL)
EUR 405

HPV-16 E6 + HPV-18 E6 (Human Papilloma Virus 16/18)

MBS4381516-5x01mgWithBSAAzideat02mgmL 5x0.1mg(WithBSA&Azideat0.2mg/mL)
EUR 1725

HPV-16 E6 + HPV-18 E6 (Human Papilloma Virus 16/18)

MBS4381516-5x01mgWithoutBSAAzideat1mgmL 5x0.1mg(WithoutBSA&Azideat1mg/mL)
EUR 1725

HPV-16 E2 Antibody

abx021892-1mg 1 mg
EUR 718.8

HPV-16 E3 Antibody

abx021893-1mg 1 mg
EUR 844.8

HPV-16 E7 Antibody

abx021896-1mg 1 mg
EUR 844.8

HPV-16 L1 Antibody

abx021897-1mg 1 mg
EUR 718.8

HPV-16 L1 Antibody

abx021898-1mg 1 mg
EUR 718.8

HPV-18 E6 Antibody

abx021899-1mg 1 mg
EUR 718.8

HPV-18 E6 Antibody

abx021900-1mg 1 mg
EUR 718.8

HPV-18 E7 Antibody

abx021901-1mg 1 mg
EUR 1053.6

HPV-16 L1 Antibody

V9117-100UG 100 ug
EUR 424.15
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V9117-20UG 20 ug
EUR 186.15
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V9117SAF-100UG 100 ug
EUR 424.15
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 E6 Antibody

V8315-100UG 100 ug
EUR 424.15
Description: Reacts with E6 protein of human papilloma virus type 16 (HPV-16). Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16.

HPV-16 E6 Antibody

V8315-20UG 20 ug
EUR 186.15
Description: Reacts with E6 protein of human papilloma virus type 16 (HPV-16). Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16.

HPV-16 E6 Antibody

V8315SAF-100UG 100 ug
EUR 424.15
Description: Reacts with E6 protein of human papilloma virus type 16 (HPV-16). Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16.

HPV-16 L1 Antibody

V3659-100UG 100 ug
EUR 349.3
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3659-20UG 20 ug
EUR 153.3
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3659IHC-7ML 7 ml
EUR 349.3
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3659SAF-100UG 100 ug
EUR 349.3
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3660-100UG 100 ug
EUR 349.3
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3660-20UG 20 ug
EUR 153.3
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3660IHC-7ML 7 ml
EUR 349.3
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3660SAF-100UG 100 ug
EUR 349.3
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3062-100UG 100 ug
EUR 424.15
Description: Reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on the basement membrane to provide initial virion attachment to target cells. Basement membrane is exposed only after epithelium trauma. Additionally, the alpha6 integrin complexed with either beta1 or beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, integrin complexed with beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, the virion enters the host cell via clathrin-mediated endocytosis and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2. [UniProt]

The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3062-20UG 20 ug
EUR 186.15
Description: Reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on the basement membrane to provide initial virion attachment to target cells. Basement membrane is exposed only after epithelium trauma. Additionally, the alpha6 integrin complexed with either beta1 or beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, integrin complexed with beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, the virion enters the host cell via clathrin-mediated endocytosis and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2. [UniProt]

The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3062SAF-100UG 100 ug
EUR 424.15
Description: Reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on the basement membrane to provide initial virion attachment to target cells. Basement membrane is exposed only after epithelium trauma. Additionally, the alpha6 integrin complexed with either beta1 or beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, integrin complexed with beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, the virion enters the host cell via clathrin-mediated endocytosis and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2. [UniProt]

The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3063-100UG 100 ug
EUR 424.15
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3063-20UG 20 ug
EUR 186.15
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3063SAF-100UG 100 ug
EUR 424.15
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3086-100UG 100 ug
EUR 424.15
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3086-20UG 20 ug
EUR 186.15
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3086CF488-100T 100 Tests
EUR 424.15
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 L1 Antibody

V3086SAF-100UG 100 ug
EUR 424.15
Description: Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

HPV-16 E6 Antibody

V3488-100UG 100 ug
EUR 424.15
Description: Reacts with E6 protein of human papilloma virus type 16 (HPV-16). Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16.

HPV-16 E6 Antibody

V3488-20UG 20 ug
EUR 186.15
Description: Reacts with E6 protein of human papilloma virus type 16 (HPV-16). Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16.

HPV-16 E6 Antibody

V3488SAF-100UG 100 ug
EUR 424.15
Description: Reacts with E6 protein of human papilloma virus type 16 (HPV-16). Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16.

HPV-16 L1 Antibody

V7185-100UG 100 ug
EUR 424.15
Description: Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies.

HPV-16 L1 Antibody

V7185-20UG 20 ug
EUR 186.15
Description: Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies.

HPV-16 L1 Antibody

V7185SAF-100UG 100 ug
EUR 424.15
Description: Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies.

HPV-16-E2 Antibody

E313558 200ul
EUR 275
Description: Available in various conjugation types.

HPV-18-E7 Antibody

E313559 100ug/200ul
EUR 295
Description: Available in various conjugation types.

HPV-16-L2 Antibody

E313934 200ul
EUR 275
Description: Available in various conjugation types.

HPV-16-E6 Antibody

E314469 100ug/200ul
EUR 295
Description: Available in various conjugation types.

HPV type 1

DAG205 1 ml
EUR 1124.4

HPV type 2

DAG206 1 ml
EUR 1057.2

HPV type 3

DAG207 1 ml
EUR 1057.2

HPV type 2

DAG4703 0.25 mg
EUR 864

HPV type 3

DAG4704 0.25 mg
EUR 864

HPV-E6-C

5-01338 4 x 1mg Ask for price

HPV-E6-M

5-01339 4 x 1mg Ask for price

HPV-E6-N

5-01340 4 x 1mg Ask for price

HPV-E7-C

5-01341 4 x 1mg Ask for price

HPV-E7-N

5-01342 4 x 1mg Ask for price

HPV-E7-N

SP-100307-1 1 mg
EUR 270

HPV-E7-C

SP-100308-1 1 mg
EUR 270

HPV-E6-N

SP-100309-1 1 mg
EUR 343.2

HPV-E6-M

SP-100310-1 1 mg
EUR 270

HPV-E6-C

SP-100311-1 1 mg
EUR 196.8

HPV-E6-C

MBS8246630-10mg 10mg
EUR 875

HPV-E6-C

MBS8246630-1mg 1mg
EUR 300

HPV-E6-C

MBS8246630-5mg 5mg
EUR 615

HPV-E6-C

MBS8246630-5x10mg 5x10mg
EUR 3845

HPV-E6-M

MBS8246631-10mg 10mg
EUR 875

HPV-E6-M

MBS8246631-1mg 1mg
EUR 300

HPV-E6-M

MBS8246631-5mg 5mg
EUR 615

HPV-E6-M

MBS8246631-5x10mg 5x10mg
EUR 3845

HPV-E6-N

MBS8246632-10mg 10mg
EUR 675

HPV-E6-N

MBS8246632-1mg 1mg
EUR 255

HPV-E6-N

MBS8246632-5mg 5mg
EUR 480

HPV-E6-N

MBS8246632-5x10mg 5x10mg
EUR 2955

HPV-E7-C

MBS8246633-10mg 10mg
EUR 875

HPV-E7-C

MBS8246633-1mg 1mg
EUR 300

HPV-E7-C

MBS8246633-5mg 5mg
EUR 615

HPV-E7-C

MBS8246633-5x10mg 5x10mg
EUR 3845

HPV-E7-N

MBS8246634-10mg 10mg
EUR 875

HPV-E7-N

MBS8246634-1mg 1mg
EUR 300

HPV-E7-N

MBS8246634-5mg 5mg
EUR 615

HPV-E7-N

MBS8246634-5x10mg 5x10mg
EUR 3845

HPV 18 Protein

MBS5316715-01mg 0.1mg
EUR 1110

HPV 18 Protein

MBS5316715-5x01mg 5x0.1mg
EUR 4840

HPV 18 Antibody

GWB-1EF6D2 0.2 mg Ask for price

HPV 11 Antibody

GWB-94FCA7 1 mg Ask for price

HPV 16 Antibody

GWB-9B0F19 1 mg Ask for price

HPV 11 Antibody

GWB-9FAE95 1 mg Ask for price

HPV 11 Antibody

GWB-A23283 1 mg Ask for price

HPV 18 Antibody

GWB-B5CD79 0.2 mg Ask for price

HPV 16 Antibody

GWB-E748CC 1 mg Ask for price

Inactivated HPV-2 Antigen

VAng-Lsx0262-inquire inquire Ask for price
Description: HPV type 2, native virus from Vero cells.

Recombinant HPV-2 Protein

VAng-Lsx0263-inquire inquire Ask for price
Description: HPV type 2, recombinant protein from MA 104 cells.

Inactivated HPV-3 Antigen

VAng-Lsx0264-inquire inquire Ask for price
Description: HPV type 3, native virus from Vero cells.

Recombinant HPV-3 Protein

VAng-Lsx0265-inquire inquire Ask for price
Description: HPV type 3, recombinant protein from MA 104 cells.

DiD-triflate-[1,1‘-Dioctadecyl-3,3,3’,3‘-tetramethylindodicarbocyanine,-triflate]

E37F22032 10-mg
EUR 465
Description: Cell-staining.-Cell-membrane-staining.

HPV-16 E1/E4 Antibody

V8338-100UG 100 ug
EUR 424.15
Description: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV16, a 'high-risk' sexually-transmitted HPV that can lead to cervical, anal, vulvar, head, neck, and penile cancer. The HPV16E1/E4 protein is expressed abundantly in cells supporting viral DNA amplification, but is lost during malignant progression. HPV16E1/E4 causes G2 cell cycle arrest by associating with and preventing the nuclear entry of Cdk1/cyclin B1 complexes. HPV16E1/E4 also interacts with cyclin A and Cdk2 during the G2 phase of the cell cycle, and this association may increase the efficiency with which HPV16E1/E4 is able to prevent mitotic entry. HPV16E1/E4 also associates with keratin intermediate filaments and causes the network to collapse.

HPV-16 E1/E4 Antibody

V8338-20UG 20 ug
EUR 186.15
Description: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV16, a 'high-risk' sexually-transmitted HPV that can lead to cervical, anal, vulvar, head, neck, and penile cancer. The HPV16E1/E4 protein is expressed abundantly in cells supporting viral DNA amplification, but is lost during malignant progression. HPV16E1/E4 causes G2 cell cycle arrest by associating with and preventing the nuclear entry of Cdk1/cyclin B1 complexes. HPV16E1/E4 also interacts with cyclin A and Cdk2 during the G2 phase of the cell cycle, and this association may increase the efficiency with which HPV16E1/E4 is able to prevent mitotic entry. HPV16E1/E4 also associates with keratin intermediate filaments and causes the network to collapse.

HPV-16 E1/E4 Antibody

V8338SAF-100UG 100 ug
EUR 424.15
Description: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV16, a 'high-risk' sexually-transmitted HPV that can lead to cervical, anal, vulvar, head, neck, and penile cancer. The HPV16E1/E4 protein is expressed abundantly in cells supporting viral DNA amplification, but is lost during malignant progression. HPV16E1/E4 causes G2 cell cycle arrest by associating with and preventing the nuclear entry of Cdk1/cyclin B1 complexes. HPV16E1/E4 also interacts with cyclin A and Cdk2 during the G2 phase of the cell cycle, and this association may increase the efficiency with which HPV16E1/E4 is able to prevent mitotic entry. HPV16E1/E4 also associates with keratin intermediate filaments and causes the network to collapse.

HPV-11 E7 Protein Antibody

abx021927-1mg 1 mg
EUR 886.8

HPV-11 E7 Protein Antibody

abx021928-1mg 1 mg
EUR 886.8

HPV-16 E7 Protein Antibody

abx021929-1mg 1 mg
EUR 886.8

HPV-16 E7 Protein Antibody

abx021930-1mg 1 mg
EUR 878.4

HPV-16 E7 Protein Antibody

abx021931-1mg 1 mg
EUR 886.8

HPV-18 E7 Protein Antibody

abx021933-1mg 1 mg
EUR 886.8

HPV-18 E7 Protein Antibody

abx021934-1mg 1 mg
EUR 886.8

Rubella Virus (strain HPV-77)

DAGA-2019 1 mg
EUR 1420.65
Description: Native

MAb to HPV 16

MBS310357-1mg 1mg
EUR 555

MAb to HPV 16

MBS310357-5x1mg 5x1mg
EUR 2395

MAb to HPV 18

MBS311728-1mg 1mg
EUR 605

MAb to HPV 18

MBS311728-5x1mg 5x1mg
EUR 2550

Recombinant HPV-10 E1 Protein

VAng-Wyb3000-inquire inquire Ask for price
Description: Human papillomavirus type 10 Replication protein E1, recombinant protein.

Recombinant HPV-10 L1 Protein

VAng-Wyb3004-inquire inquire Ask for price
Description: Human papillomavirus type 10 Major capsid protein L1, recombinant protein.

Recombinant HPV-11 E1 Protein

VAng-Wyb3006-inquire inquire Ask for price
Description: Human papillomavirus type 11 Replication protein E1, recombinant protein.

Recombinant HPV-12 L1 Protein

VAng-Wyb3019-inquire inquire Ask for price
Description: Human papillomavirus type 12 Major capsid protein L1, recombinant protein.

Recombinant HPV-12 L2 Protein

VAng-Wyb3020-inquire inquire Ask for price
Description: Human papillomavirus type 12 Minor capsid protein L2, recombinant protein.

Recombinant HPV-13 E1 Protein

VAng-Wyb3021-inquire inquire Ask for price
Description: Human papillomavirus type 13 Replication protein E1, recombinant protein.

Recombinant HPV-14 E1 Protein

VAng-Wyb3023-inquire inquire Ask for price
Description: Human papillomavirus type 14 Replication protein E1, recombinant protein.

Recombinant HPV-14 L1 Protein

VAng-Wyb3026-inquire inquire Ask for price
Description: Human papillomavirus type 14 Major capsid protein L1, recombinant protein.

Recombinant HPV-14 L2 Protein

VAng-Wyb3027-inquire inquire Ask for price
Description: Human papillomavirus type 14 Minor capsid protein L2, recombinant protein.

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