Discovery and characterization of the evolution, variation and functions of diversity-generating retroelements using thousands of genomes and metagenomes.

Diversity-generating retroelements (DGRs) are a novel household of retroelements that generate sequence range of DNA to profit their hosts by introducing variations and accelerating the evolution of goal proteins. They exist extensively in micro organism, archaea, phage and plasmid.

However, our understanding about DGRs in pure environments was nonetheless very restricted.We developed an environment friendly computational algorithm to determine DGRs, and utilized it to characterize DGRs in additional than 80,000 sequenced bacterial genomes in addition to greater than 4,000 human metagenome datasets.

In whole, we recognized 948 non-redundant DGRs, which expanded the quantity of identified DGRs in bacterial genomes and human microbiomes by about 55%, and supplied a way more complete reference for the examine of DGRs. Phylogenetic evaluation was achieved for recognized DGRs.

Discovery and characterization of the evolution, variation and functions of diversity-generating retroelements using thousands of genomes and metagenomes.
Discovery and characterization of the evolution, variation and functions of diversity-generating retroelements using thousands of genomes and metagenomes.

The putative goal genes of DGRs have been searched, and the functions of these goal genes have been investigated with a complete alignment towards the nr database.DGR system is a robust and common mechanism to generate range. DGR evolution is carefully related to the dwelling atmosphere and their cassette buildings. Furthermore, it might influence a variety of useful processes along with receptor-binding. These outcomes considerably improved our understanding about DGRs.

Diclofenac

B3505-50 50 mg
EUR 153.6

Diclofenac

HY-15036 500mg
EUR 129.6

Diclofenac [BSA]

DAG3299 1mg
EUR 1326

Diclofenac Sodium

B1457-10 10 mg
EUR 129.6
Description: Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively.Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. Diclofenac sodium (Dc), an anti-inflam

Diclofenac Sodium

B1457-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively.Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. Diclofenac sodium (Dc), an anti-inflam

Diclofenac Sodium

B1457-50 50 mg
EUR 268.8
Description: Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively.Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. Diclofenac sodium (Dc), an anti-inflam

Diclofenac Sodium

B1457-S Evaluation Sample
EUR 97.2
Description: Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively.Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. Diclofenac sodium (Dc), an anti-inflam

Diclofenac (Sodium)

HY-15037 5g
EUR 142.8

Diclofenac Potassium

B1929-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Diclofenac potassium is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac Potassium

B1929-50 50 mg
EUR 153.6
Description: Diclofenac potassium is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac Potassium

B1929-S Evaluation Sample
EUR 97.2
Description: Diclofenac potassium is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac diethylamine

20-abx185392
  • EUR 510.00
  • EUR 292.80
  • 25 g
  • 5 g

Diclofenac Diethylamine

B1928-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac Diethylamine

B1928-50 50 mg
EUR 153.6
Description: Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac Diethylamine

B1928-S Evaluation Sample
EUR 97.2
Description: Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac (diethylamine)

HY-15036A 10mM/1mL
EUR 135.6

Diclofenac sodium salt

GP9539-25G 25 g
EUR 103.2

Diclofenac sodium salt

GP9539-5G 5 g
EUR 64.8

Diclofenac sodium salt

GP9539-25 25
EUR 55.4

Diclofenac sodium salt

GP9539-5 5
EUR 23.8

Diclofenac potassium salt

GX9078-1G 1 g
EUR 93.6

Diclofenac potassium salt

GX9078-250MG 250 mg
EUR 69.6

Diclofenac potassium salt

GX9078-5G 5 g
EUR 180

Diclofenac potassium salt

GX9078-1 1
EUR 47.4

Diclofenac potassium salt

GX9078-250 250
EUR 27.8

Diclofenac potassium salt

GX9078-5 5
EUR 118.7

Diclofenac acyl-D-glucuronide

GC8579-1 1
EUR 400.9

Diclofenac acyl-D-glucuronide

GC8579-10 10
EUR 2349.1

Diclofenac acyl-D-glucuronide

GC8579-2 2
EUR 671.1

Diclofenac acyl-D-glucuronide

GC8579-5 5
EUR 1379.7

Dichlorphenamide(Diclofenamide)

E1KS2177 10mg
EUR 1804.8

Diclofensine

HY-18610A 5mg
EUR 142.8

Diclofensine (hydrochloride)

HY-18610 50mg
EUR 572.4

Diclofop

GW7731-250 250
EUR 807.2

Diclofop

GW7731-50 50
EUR 232

Diclofop methyl

S-1495 1ML
EUR 58.8

Diclofop-methyl

GW6887-1 1
EUR 152.2

Diclofop-methyl

GW6887-500 500
EUR 109.5

Dicloran

S-1497 1ML
EUR 45.6

Dicloralurea

HY-B0922 100mg
EUR 142.8

Dicloxacillin [BSA]

DAGA-187B 1mg
EUR 1076.4

Dicloxacillin [HRP]

DAGB335 0.5mg
EUR 702

Dicloxicillin-HRP

80-1145 500 ul
EUR 164.4
Description: Dicloxicillin Conjugate for use in immunoassays

Dicloxacillin Sodium

B1930-1000 1 g
EUR 134.4
Description: Dicloxacillin is a ?-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria.

Dicloxacillin Sodium

B1930-10000 10 g
EUR 584.4
Description: Dicloxacillin is a ?-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria.

Dicloxacillin Sodium

B1930-5000 5 g
EUR 340.8
Description: Dicloxacillin is a ?-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria.

Dichloroacetic acid

S-1285 1ML
EUR 45.6

1000 ug/mL Dicloran in Acetone Volume: 1mL Ampule

S-1497-AC 1ML
EUR 147.6

Dicloxacillin antibody

20-1085 100 ul
EUR 1015.2
Description: Sheep polyclonal Dicloxacillin antibody

Dicloxacillin (Sodium hydrate)

HY-B0977 10mM/1mL
EUR 151.2

2,4-Dichlorobenzoic acid

20-abx182991
  • EUR 343.20
  • EUR 276.00
  • 1 kg
  • 500 g

2,6-Dichlorobenzoic acid

20-abx183031
  • EUR 260.40
  • EUR 560.40
  • EUR 393.60
  • 100 g
  • 1 kg
  • 500 g

1,5-Dicaffeoylquinic acid

N2812-20 20 mg
EUR 686.4
Description: Extracted from honeysuckle;Store the product in sealed, cool and dry condition

1,3-Dicaffeoylquinic acid

HY-N1412 25mg
EUR 886.8

3,4-Dicaffeoylquinic acid

HY-N0057 5mg
EUR 222

4,5-Dicaffeoylquinic acid

HY-N0058 10mM/1mL
EUR 244.8

1,4-Dicaffeoylquinic acid

HY-N0358 1mg
EUR 291.6

1,5-Dicaffeoylquinic acid

TO071330 20mg Ask for price

1,5-Dicaffeoylquinic acid

TB0030 20mg
EUR 312

4,5-Dicaffeoylquinic acid

GY3789-5 5
EUR 203.4

3,5-Dicaffeoylquinic acid

GL2424-5 5
EUR 188.4

3,4-Dicaffeoylquinic acid

GY6814-5 5
EUR 165.7

4,6-Dichloronicotinic acid

20-abx183496
  • EUR 727.20
  • EUR 326.40
  • 25 g
  • 5 g

5,6-Dichloropicolinic acid

20-abx183658
  • EUR 878.40
  • EUR 326.40
  • EUR 610.80
  • 10 g
  • 1 g
  • 5 g

5,7-Dichlorokynurenic acid

B6247-10 10 mg
EUR 243.6

5,7-Dichlorokynurenic acid

B6247-50 50 mg
EUR 758.4

Dicloxacillin sodium salt monohydrate

GA0338-1G 1 g
EUR 103.2

Dicloxacillin sodium salt monohydrate

GA0338-5G 5 g
EUR 265.2

Dicloxacillin sodium salt monohydrate

GA0338-1 1
EUR 55.4

Dicloxacillin sodium salt monohydrate

GA0338-5 5
EUR 189.8

23-Dichloropropionic acid

S-4305 1ML
EUR 150

23-Dichloropropionic Acid

S-4305-MTBE 1ML
EUR 92.4

3,6-Dichlorotrimellitic acid

HY-D0828 100mg
EUR 639.6

3,6-Dichlorotrimellitic acid

GW4063-1 1
EUR 947.7

3,6-Dichlorotrimellitic acid

GW4063-250 250
EUR 353.2

Cyanine7 dicarboxylic acid, 100 mg

1512-100mg 100 mg
EUR 1006.8

2,4-Dichlorophenoxyacetic acid

20-abx184997
  • EUR 226.80
  • EUR 360.00
  • EUR 292.80
  • 100 g
  • 1 kg
  • 500 g

3,4-Dichlorophenylboronic Acid

20-abx180382
  • EUR 410.40
  • EUR 2264.40
  • EUR 260.40
  • EUR 1245.60
  • EUR 210.00
  • 100 g
  • 1 kg
  • 25 g
  • 500 g
  • 5 g

2,4-Dichlorophenoxyacetic acid

D069-25G 25 g
EUR 60

2,4-Dichlorophenoxyacetic acid

D069-4x25G 4 x 25 g
EUR 63.6

2,4-Dichlorophenoxyacetic acid

GK6386-100G 100 g
EUR 60

2,4-Dichlorophenoxyacetic acid

GK6386-1KG 1 kg
EUR 160.8

2,4-Dichlorophenoxyacetic acid

GK6386-250G 250 g
EUR 74.4

2,4-Dichlorophenoxyacetic acid

GK6386-25G 25 g
EUR 51.6

2,4-Dichlorophenoxyacetic acid

GK6386-500G 500 g
EUR 108

2,4-Dichlorophenoxyacetic acid

GK6386-1 1
EUR 102.7

2,4-Dichlorophenoxyacetic acid

GK6386-100 100
EUR 19.8

2,4-Dichlorophenoxyacetic acid

GK6386-25 25
EUR 13.9

2,4-Dichlorophenoxyacetic acid

GK6386-250 250
EUR 31.7

2,4-Dichlorophenoxyacetic acid

GK6386-500 500
EUR 59.3

3,5-Dichlorobenzeneboronic Acid

20-abx181094
  • EUR 526.80
  • EUR 292.80
  • EUR 226.80
  • 100 g
  • 25 g
  • 5 g

2,4-Dichlorobenzeneboronic Acid

20-abx181645
  • EUR 460.80
  • EUR 276.00
  • EUR 226.80
  • 100 g
  • 25 g
  • 5 g

Biphenyl-4,4'-Dicarboxylic Acid

20-abx188617
  • EUR 326.40
  • EUR 678.00
  • 100 g
  • 500 g

Pyridine-2,3-dicarboxylic acid

20-abx184330
  • EUR 276.00
  • EUR 226.80
  • EUR 460.80
  • 100 g
  • 25 g
  • 500 g

Pyridine-2,4-dicarboxylic acid

20-abx184331
  • EUR 243.60
  • EUR 543.60
  • EUR 309.60
  • 1 g
  • 25 g
  • 5 g

Dichloroacetic acid sodium salt

GE0235-100G 100 g
EUR 322.8

24-Dichlorophenyl acetic acid

S-1420 1ML
EUR 84

Dichloroacetic acid sodium salt

GE0235-10 10
EUR 38.8

Dichloroacetic acid sodium salt

GE0235-100 100
EUR 237.2

Dichloroacetic acid sodium salt

GE0235-50 50
EUR 135.6

PEG3 dicarboxylic acid, 10 g

1715-10g 10 g
EUR 1092

PEG3 dicarboxylic acid, 1 g

1715-1g 1 g
EUR 423.6

PEG3 dicarboxylic acid, 5 g

1715-5g 5 g
EUR 735.6

4,6-Pyrimidine Dicarboxylic Acid

20-abx185183
  • EUR 393.60
  • EUR 744.00
  • 10 g
  • 50 g

2, 4-Dichlorophenoxyacetic acid

20-abx082315
  • EUR 260.40
  • EUR 210.00
  • 25 g
  • 5 g

naphthalene-2,7-dicarboxylic acid

20-abx182588
  • EUR 1663.20
  • EUR 777.60
  • 1 g
  • 250 mg

1,1‐CYCLOPROPANE DICARBOXYXLIC ACID

503021 each Ask for price

Sulfo-Cyanine7.5 dicarboxylic acid, 100 mg

1382-100mg 100 mg
EUR 1711.2

sulfo-Cyanine7 dicarboxylic acid, 100 mg

1497-100mg 100 mg
EUR 1711.2

Cyanine7 dicarboxylic acid, 1 mg

1512-1mg 1 mg
EUR 129.6

Cyanine7 dicarboxylic acid, 25 mg

1512-25mg 25 mg
EUR 379.2

Cyanine7 dicarboxylic acid, 50 mg

1512-50mg 50 mg
EUR 601.2

Cyanine7 dicarboxylic acid, 5 mg

1512-5mg 5 mg
EUR 218.4

Dichloroisocyanuric acid sodium salt

GK1713-25 25
EUR 19.1

2, 4-Dichlorophenoxy acetic acid

DB0166 100g
EUR 77.41

tetrahydropyran-4,4-dicarboxylic acid

20-abx180899
  • EUR 460.80
  • EUR 994.80
  • 1 g
  • 5 g

2-Amino-3,5-dichlorobenzoic acid

20-abx181010
  • EUR 560.40
  • EUR 360.00
  • EUR 260.40
  • 100 g
  • 25 g
  • 5 g

2,6‐DICHLORO‐5‐FLUORONICOTINIC ACID

904012 each Ask for price

Okadaic acid, free acid

OL1198 50ug
EUR 231.22

3,6-Dichloro-2-methoxybenzoic acid

20-abx185108
  • EUR 1262.40
  • EUR 627.60
  • EUR 309.60
  • 100 g
  • 25 g
  • 5 g

5,7-Dichlorokynurenic acid sodium salt

B7478-10 10 mg
EUR 243.6

5,7-Dichlorokynurenic acid sodium salt

B7478-50 50 mg
EUR 837.6

24-D (24-Dichlorophenoxyacetic acid)

S-1045 1ML
EUR 45.6

35-Dichlorobenzoic acid methyl ester

S-1346 1ML
EUR 148.8

Fumalic acid(Ferulic acid)

E1KS2300 50mg
EUR 390

2,3-Dichloropyridine-4-Boronic Acid

20-abx182962
  • EUR 1730.40
  • EUR 477.60
  • EUR 760.80
  • 100 g
  • 10 g
  • 25 g

2,5-Dichloropyridine-4-Boronic Acid

20-abx181656
  • EUR 693.60
  • EUR 260.40
  • EUR 1279.20
  • EUR 493.20
  • 10 g
  • 1 g
  • 25 g
  • 5 g

Octanoic acid (Caorylic acid)

O5678 250ml
EUR 80.88

3,6-Dichloro-2-hydroxy benzoic acid

20-abx180033
  • EUR 1228.80
  • EUR 3300.00
  • 1 g
  • 5 g

3,5-Dichloropyrazine-2-Carboxylic Acid

20-abx181868
  • EUR 1045.20
  • EUR 477.60
  • 1 g
  • 250 mg

3,6-Dichloropyridine-2-carboxylic acid

20-abx181875
  • EUR 1796.40
  • EUR 410.40
  • EUR 610.80
  • EUR 326.40
  • 100 g
  • 10 g
  • 25 g
  • 5 g

Trans-Cyclopentane-1,2-Dicarboxylic Acid

abx188918-100g 100 g
EUR 376.8

2,5-Dichlorothiophene-3-carboxylic acid

20-abx181657
  • EUR 777.60
  • EUR 393.60
  • 100 g
  • 25 g

Sulfo-Cyanine7.5 dicarboxylic acid, 25 mg

1382-25mg 25 mg
EUR 615.6

Sulfo-Cyanine7.5 dicarboxylic acid, 50 mg

1382-50mg 50 mg
EUR 1105.2

Sulfo-Cyanine7.5 dicarboxylic acid, 5 mg

1382-5mg 5 mg
EUR 280.8

sulfo-Cyanine7 dicarboxylic acid, 1 mg

1497-1mg 1 mg
EUR 129.6

sulfo-Cyanine7 dicarboxylic acid, 25 mg

1497-25mg 25 mg
EUR 615.6

sulfo-Cyanine7 dicarboxylic acid, 50 mg

1497-50mg 50 mg
EUR 1105.2

sulfo-Cyanine7 dicarboxylic acid, 5 mg

1497-5mg 5 mg
EUR 280.8

3,5-Dichloro-4-methoxyphenylboronic acid

20-abx181867
  • EUR 393.60
  • EUR 895.20
  • 1 g
  • 5 g

3,6-Dichloropyridazine-4-carboxylic acid

20-abx180391
  • EUR 1111.20
  • EUR 510.00
  • 25 g
  • 5 g

Bicyclo[1.1.1]pentane-1,3-dicarboxylic acid

abx185359-1g 1 g
EUR 1446

3,4-Dichloroisothiazole-5-carboxylic acid

20-abx185098
  • EUR 292.80
  • EUR 994.80
  • EUR 460.80
  • 1 g
  • 25 g
  • 5 g

DL-Maleic acid (Toxilic acid)

MA0333 250g
EUR 77.4

D-Glucuronic acid, free acid

GB0482 5g
EUR 186.19

Dichloroisocyanuric acid sodium salt dihydrate

GK1784-100G 100 g
EUR 56.4

Dichloroisocyanuric acid sodium salt dihydrate

GK1784-1KG 1 kg
EUR 112.8

Dichloroisocyanuric acid sodium salt dihydrate

GK1784-250G 250 g
EUR 64.8

Dichloroisocyanuric acid sodium salt dihydrate

GK1784-500G 500 g
EUR 84

Dichloroisocyanuric acid sodium salt dihydrate

GK1784-50G 50 g
EUR 50.4

Dichloroisocyanuric acid sodium salt dihydrate

GK1784-1 1
EUR 63.3

Dichloroisocyanuric acid sodium salt dihydrate

GK1784-100 100
EUR 16.6

Dichloroisocyanuric acid sodium salt dihydrate

GK1784-250 250
EUR 23.8

Dichloroisocyanuric acid sodium salt dihydrate

GK1784-50 50
EUR 13

Dichloroisocyanuric acid sodium salt dihydrate

GK1784-500 500
EUR 39.4

5-Bromo-Pyridine-2,3-Dicarboxylic Acid

20-abx183703
  • EUR 309.60
  • EUR 376.80
  • 10 g
  • 25 g

7-Diethylaminocoumarin-3,4-dicarboxylic acid

GW2126-1 1
EUR 2323.8

7-Diethylaminocoumarin-3,4-dicarboxylic acid

GW2126-100 100
EUR 317.3

24-Dichlorophenyl acetic acid methyl ester

S-1421 1ML
EUR 224.4

Tide Quencherâ„¢ 3 acid [TQ3 acid]

2220-100mg 100 mg
EUR 222
Description: TQ3 is designed to be a superior quencher to TAMRA, TF3 and Cy3.

Tide Quencherâ„¢ 1 acid [TQ1 acid]

2190-100mg 100 mg
EUR 222
Description: TQ1 is designed to be a superior quencher alternative to DABCYL.

Tide Quencherâ„¢ 2 acid [TQ2 acid]

2200-100mg 100 mg
EUR 222
Description: TQ2 is designed to be a superior quencher to FAM, HEX, TET, JOE, TF2 and rhodamine 6G.

3,5-Dichloro-4-pyridone-1-acetic acid

20-abx180389
  • EUR 811.20
  • EUR 410.40
  • EUR 260.40
  • 100 g
  • 25 g
  • 5 g

MUCOBROMIC ACID (2,3‐ DIBROMOMALEALDEHYDIC ACID)

613004 each Ask for price

Tide Quencherâ„¢ 3WS acid [TQ3WS acid]

2227-5mg 5 mg
EUR 222
Description: TQ3WS is designed to be a superior quencher to TAMRA, TF3 and Cy3.

Tide Quencherâ„¢ 2WS acid [TQ2WS acid]

2050-25mg 25 mg
EUR 222
Description: TQ2WS is designed to be a superior quencher to FAM, HEX, TET, JOE, TF2 and rhodamine 6G.

Tide Quencherâ„¢ 4WS acid [TQ4WS acid]

2060-5mg 5 mg
EUR 222
Description: TQ4WS is designed to be a superior quencher to ROX, TF4 and Texas Red®.

Tide Quencherâ„¢ 5WS acid [TQ5WS acid]

2075-5mg 5 mg
EUR 222
Description: TQ5WS is designed to be a superior quencher to Cy5, TF5 and Cy5.5.

Tide Quencherâ„¢ 6WS acid [TQ6WS acid]

2090-5mg 5 mg
EUR 334
Description: TQ6WS is designed to be a superior quencher to Cy5.5, TF6 and Alexa Fluor 680.

Tide Quencherâ„¢ 7WS acid [TQ7WS acid]

2105-5mg 5 mg
EUR 558
Description: TQ7WS is designed to be a superior quencher to Cy7, TF7 and Alexa Fluor 750.

2,4-Dichloropyrimidine-5-carboxylic acid amide

20-abx185711
  • EUR 678.00
  • EUR 526.80
  • EUR 1646.40
  • 1 g
  • 250 mg
  • 5 g

Tide Quencher™ 1 acid [TQ1 acid]

2190 100 mg
EUR 222

Tide Quencher™ 2 acid [TQ2 acid]

2200 100 mg
EUR 222

Tide Quencher™ 3 acid [TQ3 acid]

2220 100 mg
EUR 222

Rat Uric Acid(Uric Acid) ELISA Kit

YLA1447RA-48T 48T
EUR 465

Rat Uric Acid(Uric Acid) ELISA Kit

YLA1447RA-96T 96T
EUR 600

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