Discovery and characterization of the evolution, variation and functions of diversity-generating retroelements using thousands of genomes and metagenomes.

Diversity-generating retroelements (DGRs) are a novel household of retroelements that generate sequence range of DNA to profit their hosts by introducing variations and accelerating the evolution of goal proteins. They exist extensively in micro organism, archaea, phage and plasmid.

However, our understanding about DGRs in pure environments was nonetheless very restricted.We developed an environment friendly computational algorithm to determine DGRs, and utilized it to characterize DGRs in additional than 80,000 sequenced bacterial genomes in addition to greater than 4,000 human metagenome datasets.

In whole, we recognized 948 non-redundant DGRs, which expanded the quantity of identified DGRs in bacterial genomes and human microbiomes by about 55%, and supplied a way more complete reference for the examine of DGRs. Phylogenetic evaluation was achieved for recognized DGRs.

The putative goal genes of DGRs have been searched, and the functions of these goal genes have been investigated with a complete alignment towards the nr database.DGR system is a robust and common mechanism to generate range. DGR evolution is carefully related to the dwelling atmosphere and their cassette buildings. Furthermore, it might influence a variety of useful processes along with receptor-binding. These outcomes considerably improved our understanding about DGRs.

Diclofenac Acid
TRC-D436465-1G	Toronto Research Chemicals	1 g	Ask for price

Diclofenac Carboxylic Acid (Diclofenac Metabolite)
D435670	Toronto Research Chemicals	10mg	EUR 164
Description: 13625-57-5

Diclofenac Carboxylic Acid (Diclofenac Metabolite)
MBS6061746-5mg	MyBiosource	5(mg	EUR 485

Diclofenac Carboxylic Acid (Diclofenac Metabolite)
MBS6061746-5x5mg	MyBiosource	5x5(mg	EUR 2025

Diclofenac Carboxylic Acid (Diclofenac Metabolite)
TRC-D435670-5MG	Toronto Research Chemicals	5 mg	Ask for price

Diclofenac Carboxylic Acid (Diclofenac Metabolite)
TRC-D435670-10MG	Toronto Research Chemicals	10 mg	Ask for price

Diclofenac Carboxylic Acid (Diclofenac Metabolite)
TRC-D435670-25MG	Toronto Research Chemicals	25 mg	Ask for price

Diclofenac free acid
317604	MedKoo Biosciences	10.0g	EUR 150

Diclofenac, free acid
GX8255	Glentham Life Sciences	25g	EUR 57.9

Diclofenac, free acid
GX8255-25	Glentham Life Sciences	25	EUR 63.3

Diclofenac, free acid
GX8255-25G	Glentham Life Sciences	25 g	EUR 112.8

Diclofenac Alcohol (Diclofenac Impurity)
D435698	Toronto Research Chemicals	25mg	EUR 115
Description: 27204-57-5

Diclofenac Alcohol (Diclofenac Impurity)
MBS6062591-10mg	MyBiosource	10mg	EUR 790

Diclofenac Alcohol (Diclofenac Impurity)
MBS6062591-25mg	MyBiosource	25mg	EUR 970

Diclofenac Alcohol (Diclofenac Impurity)
MBS6062591-5mg	MyBiosource	5(mg	EUR 620

Diclofenac Alcohol (Diclofenac Impurity)
MBS6062591-5x25mg	MyBiosource	5x25mg	EUR 4210

Diclofenac Alcohol (Diclofenac Impurity)
TRC-D435698-50MG	Toronto Research Chemicals	50 mg	Ask for price

Diclofenac Alcohol (Diclofenac Impurity)
TRC-D435698-25MG	Toronto Research Chemicals	25 mg	Ask for price

Diclofenac Alcohol (Diclofenac Impurity)
TRC-D435698-5MG	Toronto Research Chemicals	5 mg	Ask for price

Diclofenac
B3505-10000	ApexBio	10g	EUR 59.2
Description: Neuroscience|COX

Diclofenac
B3505-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 272
Description: Neuroscience|COX

Diclofenac
B3505-50	ApexBio	50 mg	EUR 153.6

Diclofenac
B3505-5000	ApexBio	5g	EUR 40
Description: Neuroscience|COX

Diclofenac
HY-15036	MedChemExpress	500mg	EUR 54.11
Description: Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].

Diclofenac
MBS3842525-500mg	MyBiosource	500mg	EUR 135

Diclofenac
MBS3842525-5x500mg	MyBiosource	5x500mg	EUR 600

Diclofenac
T0196-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Diclofenac

Diclofenac
T0196-1g	TargetMol Chemicals	1g	Ask for price
Description: Diclofenac

Diclofenac
T0196-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Diclofenac

Diclofenac
T0196-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Diclofenac

Diclofenac
T0196-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Diclofenac

Diclofenac-13C6
D436449	Toronto Research Chemicals	10mg	EUR 402
Description: 1261393-71-8

Diclofenac-13C6
HY-15036S1	MedChemExpress	1mg	Ask for price
Description: Diclofenac-13C6 is the 13C6 labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

Diclofenac-13C6
TRC-D436449-5MG	Toronto Research Chemicals	5 mg	Ask for price

Diclofenac-13C6
TRC-D436449-10MG	Toronto Research Chemicals	10 mg	Ask for price

Diclofenac [BSA]
DAG3299	Creative Diagnostics	1mg	EUR 887.25
Description: Synthetic

Diclofenac [KLH]
DAGA-256k	Creative Diagnostics	1 mg	EUR 2089.5
Description: Synthetic

Diclofenac-d4
D436452	Toronto Research Chemicals	10mg	EUR 261
Description: 153466-65-0

Diclofenac-d4
HY-15036S	MedChemExpress	1 mg	EUR 405.85
Description: Diclofenac-d4 is the deuterium labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].

Diclofenac-d4
TRC-D436452-10MG	Toronto Research Chemicals	10 mg	Ask for price

Diclofenac-d4
TRC-D436452-1MG	Toronto Research Chemicals	1 mg	Ask for price

Diclofenac Amide
D436440	Toronto Research Chemicals	100mg	EUR 125
Description: 15362-40-0

Diclofenac Amide
MBS3602170-10mg	MyBiosource	10mg	EUR 305

Diclofenac Amide
MBS3602170-25mg	MyBiosource	25mg	EUR 390

Diclofenac Amide
MBS3602170-2mg	MyBiosource	2mg	EUR 220

Diclofenac Amide
MBS3602170-50mg	MyBiosource	50mg	EUR 595

Diclofenac Amide
MBS3602170-5mg	MyBiosource	5mg	EUR 250

Diclofenac Amide
MBS6046859-100mg	MyBiosource	100mg	EUR 960

Diclofenac Amide
MBS6046859-10mg	MyBiosource	10mg	EUR 660

Diclofenac Amide
MBS6046859-5mg	MyBiosource	5(mg	EUR 470

Diclofenac Amide
MBS6046859-5x100mg	MyBiosource	5x100(mg	EUR 4180

Diclofenac Amide
MBS577760-10mg	MyBiosource	10mg	EUR 240

Diclofenac Amide
MBS577760-1mg	MyBiosource	1mg	EUR 145

Diclofenac Amide
MBS577760-25mg	MyBiosource	25mg	EUR 325

Diclofenac Amide
MBS577760-2mg	MyBiosource	2mg	EUR 155

Diclofenac Amide
MBS577760-5mg	MyBiosource	5mg	EUR 180

Diclofenac Amide
T0643-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Diclofenac Amide

Diclofenac Amide
T0643-1g	TargetMol Chemicals	1g	Ask for price
Description: Diclofenac Amide

Diclofenac Amide
T0643-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Diclofenac Amide

Diclofenac Amide
T0643-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Diclofenac Amide

Diclofenac Amide
T0643-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Diclofenac Amide

Diclofenac Amide
TRC-D436440-100MG	Toronto Research Chemicals	100 mg	Ask for price

Diclofenac Amide
TRC-D436440-25MG	Toronto Research Chemicals	25 mg	Ask for price

Diclofenac Amide
TRC-D436440-250MG	Toronto Research Chemicals	250 mg	Ask for price

Diclofenac sodium
573726	MedKoo Biosciences	5.0g	EUR 225

Diclofenac Sodium
B1457-10	ApexBio	10 mg	EUR 129.6
Description: Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively.Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. Diclofenac sodium (Dc), an anti-inflam

Diclofenac Sodium
B1457-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 40
Description: Neuroscience|COX

Diclofenac Sodium
B1457-50	ApexBio	50 mg	EUR 268.8
Description: Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively.Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. Diclofenac sodium (Dc), an anti-inflam

Diclofenac Sodium
B1457-5000	ApexBio	5g	EUR 40
Description: Neuroscience|COX

Diclofenac Sodium
B1457-S	ApexBio	Evaluation Sample	EUR 24
Description: Neuroscience|COX

Diclofenac (Sodium)
HY-15037	MedChemExpress	5g	EUR 59.52
Description: Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].

Diclofenac sodium
MBS3602146-100mg	MyBiosource	100mg	EUR 325

Diclofenac sodium
MBS3602146-10mg	MyBiosource	10mg	EUR 200

Diclofenac sodium
MBS3602146-200mg	MyBiosource	200mg	EUR 455

Diclofenac sodium
MBS3602146-50mg	MyBiosource	50mg	EUR 265

Diclofenac sodium
MBS3602146-5x200mg	MyBiosource	5x200mg	EUR 1735

Diclofenac sodium
MBS385374-1mLinDMSO	MyBiosource	1mL(inDMSO)	EUR 160

Diclofenac sodium
MBS385374-500mg	MyBiosource	500mg	EUR 135

Diclofenac sodium
MBS385374-5x1mLinDMSO	MyBiosource	5x1mL(inDMSO)	EUR 710

Diclofenac sodium
MBS577544-500mg	MyBiosource	500mg	EUR 145

Diclofenac sodium
MBS577544-5x500mg	MyBiosource	5x500mg	EUR 500

Diclofenac sodium
T1555-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Diclofenac sodium

Diclofenac sodium
T1555-1g	TargetMol Chemicals	1g	Ask for price
Description: Diclofenac sodium

Diclofenac sodium
T1555-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Diclofenac sodium

Diclofenac sodium
T1555-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Diclofenac sodium

Diclofenac sodium
T1555-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Diclofenac sodium

Diclofenac sodium
D4900	Solarbio Life Science	Ask for price Ask for price	25 g 100 g

Diclofenac Allergen
51-98	Astra Biotech	1 Each	Ask for price

Diclofenac-13C6 (sodium)
HY-15037S2	MedChemExpress	10 mg	EUR 1573.62
Description: Diclofenac-13C6 (Sodium) is the 13C6 labeled Diclofenac (Sodium). Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

Diclofenac epolamine
413646	MedKoo Biosciences	250.0mg	EUR 345

Diclofenac potassium
412436	MedKoo Biosciences	50.0mg	EUR 250

Diclofenac Potassium
B1929-10000	ApexBio	10g	EUR 59.2
Description: nonsteroidal anti-inflammatory drug

Diclofenac Potassium
B1929-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 40
Description: nonsteroidal anti-inflammatory drug

Diclofenac Potassium
B1929-50	ApexBio	50 mg	EUR 153.6
Description: Diclofenac potassium is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac Potassium
B1929-5000	ApexBio	5g	EUR 40
Description: nonsteroidal anti-inflammatory drug

Diclofenac Potassium
B1929-S	ApexBio	Evaluation Sample	EUR 24
Description: nonsteroidal anti-inflammatory drug

Diclofenac Epolamine
D436470	Toronto Research Chemicals	2.5g	EUR 184
Description: 119623-66-4

Diclofenac Epolamine
C6408-25	ApexBio	25mg	EUR 51.2

Diclofenac (potassium)
HY-15038	MedChemExpress	100 mg	EUR 75.76
Description: Diclofenac potassium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].

Diclofenac epolamine
HY-109547	MedChemExpress	10 mg	EUR 151.52
Description: Flector Patch (Diclofenac epolamine) is a non-steroidal anti-inflammatory drug (NSAID)[1]. Flector Patch is used for relieving arthritis Pain, acute Pain, osteoarthritis, and actinic Keratosis. Flector Patch has good skin absorption characteristics without local adverse reactions and allergies[2].

Diclofenac Potassium
MBS3608061-100mg	MyBiosource	100mg	EUR 245

Diclofenac Potassium
MBS3608061-200mg	MyBiosource	200mg	EUR 305

Diclofenac Potassium
MBS3608061-25mg	MyBiosource	25mg	EUR 200

Diclofenac Potassium
MBS3608061-50mg	MyBiosource	50mg	EUR 215

Diclofenac Potassium
MBS3608061-5x200mg	MyBiosource	5x200mg	EUR 1050

Diclofenac Epolamine
MBS5756830-100mg	MyBiosource	100mg	EUR 300

Diclofenac Epolamine
MBS5756830-10mg	MyBiosource	10mg	EUR 155

Diclofenac Epolamine
MBS5756830-200mg	MyBiosource	200mg	EUR 400

Diclofenac Epolamine
MBS5756830-25mg	MyBiosource	25mg	EUR 190

Diclofenac Epolamine
MBS5756830-50mg	MyBiosource	50mg	EUR 235

Diclofenac Potassium
MBS579012-100mg	MyBiosource	100mg	EUR 180

Diclofenac Potassium
MBS579012-200mg	MyBiosource	200mg	EUR 240

Diclofenac Potassium
MBS579012-25mg	MyBiosource	25mg	EUR 145

Diclofenac Potassium
MBS579012-50mg	MyBiosource	50mg	EUR 155

Diclofenac Potassium
MBS579012-5x200mg	MyBiosource	5x200mg	EUR 930

Diclofenac Epolamine
T22307-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Diclofenac Epolamine

Diclofenac Epolamine
T22307-1g	TargetMol Chemicals	1g	Ask for price
Description: Diclofenac Epolamine

Diclofenac Epolamine
T22307-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Diclofenac Epolamine

Diclofenac Epolamine
T22307-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Diclofenac Epolamine

Diclofenac Epolamine
T22307-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Diclofenac Epolamine

Diclofenac Potassium
T6470-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Diclofenac Potassium

Diclofenac Potassium
T6470-1g	TargetMol Chemicals	1g	Ask for price
Description: Diclofenac Potassium

Diclofenac Potassium
T6470-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Diclofenac Potassium

Diclofenac Potassium
T6470-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Diclofenac Potassium

Diclofenac Potassium
T6470-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Diclofenac Potassium

Diclofenac Epolamine
TRC-D436470-2.5G	Toronto Research Chemicals	2.5 g	Ask for price

Diclofenac Epolamine
TRC-D436470-250MG	Toronto Research Chemicals	250 mg	Ask for price

Diclofenac diethylamine
574522	MedKoo Biosciences	1.0g	EUR 205

Diclofenac Diethylamine
B1928-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 44
Description: non-selective COX inhibitor

Diclofenac Diethylamine
B1928-50	ApexBio	50 mg	EUR 153.6
Description: Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac Diethylamine
B1928-5000	ApexBio	5g	EUR 40
Description: non-selective COX inhibitor

Diclofenac Diethylamine
B1928-S	ApexBio	Evaluation Sample	EUR 24
Description: non-selective COX inhibitor

Diclofenac diethylamine
20-abx185392	Abbexa	Ask for price Ask for price	5 g 25 g

Diclofenac (diethylamine)
HY-15036A	MedChemExpress	10mM/1mL	EUR 59.52
Description: Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac diethylamine induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].

Diclofenac diethylamine
MBS3605948-100mg	MyBiosource	100mg	EUR 245

Diclofenac diethylamine
MBS3605948-200mg	MyBiosource	200mg	EUR 305

Diclofenac diethylamine
MBS3605948-25mg	MyBiosource	25mg	EUR 200

Diclofenac diethylamine
MBS3605948-50mg	MyBiosource	50mg	EUR 215

Diclofenac diethylamine
MBS3605948-5x200mg	MyBiosource	5x200mg	EUR 1050

Diclofenac diethylamine
MBS3841710-500mg	MyBiosource	500mg	EUR 135

Diclofenac diethylamine
MBS3841710-5x500mg	MyBiosource	5x500mg	EUR 600

Diclofenac diethylamine
MBS577825-100mg	MyBiosource	100mg	EUR 130

Diclofenac diethylamine
MBS577825-500mg	MyBiosource	500mg	EUR 145

Diclofenac diethylamine
MBS577825-50mg	MyBiosource	50mg	EUR 120

Diclofenac diethylamine
MBS577825-5x500mg	MyBiosource	5x500mg	EUR 500

Diclofenac diethylamine
T0432-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Diclofenac diethylamine

Diclofenac diethylamine
T0432-1g	TargetMol Chemicals	1g	Ask for price
Description: Diclofenac diethylamine

Diclofenac diethylamine
T0432-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Diclofenac diethylamine

Diclofenac diethylamine
T0432-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Diclofenac diethylamine

Diclofenac diethylamine
T0432-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Diclofenac diethylamine

4’-Hydroxy Diclofenac
H825225	Toronto Research Chemicals	10mg	EUR 526
Description: 64118-84-9

3’-Hydroxy Diclofenac
H825725	Toronto Research Chemicals	25mg	EUR 11200
Description: 69002-85-3

4'-Hydroxy diclofenac
HY-15550	MedChemExpress	1 mg	EUR 649.36
Description: 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties[1][2].

4'-Hydroxy Diclofenac
MBS6096003-10mg	MyBiosource	10mg	EUR 2005

4'-Hydroxy Diclofenac
MBS6096003-1mg	MyBiosource	1(mg	EUR 505

4'-Hydroxy Diclofenac
MBS6096003-5mg	MyBiosource	5mg	EUR 1130

4'-Hydroxy Diclofenac
MBS6096003-5x10mg	MyBiosource	5x10(mg	EUR 8865

4'-Hydroxy diclofenac
T19819-10mg	TargetMol Chemicals	10mg	Ask for price
Description: 4'-Hydroxy diclofenac

4'-Hydroxy diclofenac
T19819-1g	TargetMol Chemicals	1g	Ask for price
Description: 4'-Hydroxy diclofenac

4'-Hydroxy diclofenac
T19819-1mg	TargetMol Chemicals	1mg	Ask for price
Description: 4'-Hydroxy diclofenac

4'-Hydroxy diclofenac
T19819-50mg	TargetMol Chemicals	50mg	Ask for price
Description: 4'-Hydroxy diclofenac

4'-Hydroxy diclofenac
T19819-5mg	TargetMol Chemicals	5mg	Ask for price
Description: 4'-Hydroxy diclofenac

4’-Hydroxy Diclofenac
TRC-H825225-1MG	Toronto Research Chemicals	1 mg	Ask for price

3’-Hydroxy Diclofenac
TRC-H825725-25MG	Toronto Research Chemicals	25 mg	Ask for price

4’-Hydroxy Diclofenac
TRC-H825225-10MG	Toronto Research Chemicals	10 mg	Ask for price

4’-Hydroxy Diclofenac
TRC-H825225-5MG	Toronto Research Chemicals	5 mg	Ask for price

Diclofenac Sodium Salt
D436450	Toronto Research Chemicals	10g	EUR 63
Description: 15307-79-6

Diclofenac Ethyl Ester
D436495	Toronto Research Chemicals	100mg	EUR 148
Description: 15307-77-4

5-Hydroxy Diclofenac
H825230	Toronto Research Chemicals	1mg	EUR 221
Description: 69002-84-2

Diclofenac-d4 (sodium)
HY-15037S1	MedChemExpress	1 mg	EUR 919.93
Description: Diclofenac-d4 (sodium) is the deuterium labeled Diclofenac sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].

Diclofenac sodium salt
GP9539	Glentham Life Sciences	5g	EUR 50.75

Diclofenac sodium salt
GP9539-25	Glentham Life Sciences	25	EUR 55.4

Diclofenac sodium salt
GP9539-25G	Glentham Life Sciences	25 g	EUR 103.2

Diclofenac sodium salt
GP9539-5	Glentham Life Sciences	5	EUR 23.8

Diclofenac sodium salt
GP9539-5G	Glentham Life Sciences	5 g	EUR 64.8

5-Hydroxy Diclofenac
MBS6032367-1mg	MyBiosource	1(mg	EUR 545

5-Hydroxy Diclofenac
MBS6032367-5x1mg	MyBiosource	5x1mg	EUR 2310