Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing.

Transcription of transposable parts is tightly regulated to stop genome injury. KRAB domain-containing zinc finger proteins (KRAB-ZFPs) and KRAB-associated protein 1 (KAP1/TRIM28) play a key position in regulating retrotransposons. KRAB-ZFPs acknowledge particular retrotransposon sequences and recruit KAP1, inducing the meeting of an epigenetic silencing advanced, with chromatin transforming actions that repress transcription of the focused retrotransposon and adjoining genes.

Our biophysical and structural knowledge present that the tripartite motif (TRIM) of KAP1 kinds antiparallel dimers, which additional assemble into tetramers and higher-order oligomers in a concentration-dependent method. Structure-based mutations within the B-box 1 area forestall higher-order oligomerization with out important loss of retrotransposon silencing exercise, indicating that, in distinction to different TRIM-family proteins, self-assembly just isn’t important for KAP1 operate.

The crystal construction of the KAP1 TRIM dimer identifies the KRAB area binding website within the coiled-coil area close to the dyad. Mutations at this website abolished KRAB binding and transcriptional silencing exercise of KAP1.

This work identifies the interplay interfaces within the KAP1 TRIM accountable for self-association and KRAB binding and establishes their position in retrotransposon silencing.

Dichlorofluorescein I
T131607-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Dichlorofluorescein I

Dichlorofluorescein I
T131607-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Dichlorofluorescein I

2',7'-Dichlorofluorescein
11716-71	NACALAI TESQUE	1G	EUR 17.15

2'',7''-Dichlorofluorescein
GT8033	Glentham Life Sciences	1g	EUR 20.32

2'',7''-Dichlorofluorescein
GT8033-1	Glentham Life Sciences	1	EUR 22.1

2',7'-Dichlorofluorescein
GT8033-1G	Glentham Life Sciences	1 g	EUR 62.4

2 7-Dichlorofluorescein
D15310	Pfaltz & Bauer	5G	EUR 116.09
Description: CAS N° 76-54-0

2, 7-Dichlorofluorescein
DD1220	Bio Basic	5g	EUR 82.97

USP Sol. Dichlorofluorescein TS - 100ML
USP2301	Scientific Laboratory Supplies	100ML	EUR 375.3

USP Sol. Dichlorofluorescein TS - 500ML
USP2305	Scientific Laboratory Supplies	500ML	EUR 334.8

2',7'-Dichlorofluorescein diacetate
D434533	Toronto Research Chemicals	1g	EUR 59
Description: 2044-85-1

2′,7′-Dichlorofluorescein diacetate
HY-126793	MedChemExpress	100 mg	EUR 54.11
Description: 2′,7′-Dichlorofluorescein diacetate (DCFH2-DA) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon[1].

2',7'-Dichlorofluorescein diacetate
T20684-10mg	TargetMol Chemicals	10mg	Ask for price
Description: 2',7'-Dichlorofluorescein diacetate

2',7'-Dichlorofluorescein diacetate
T20684-1g	TargetMol Chemicals	1g	Ask for price
Description: 2',7'-Dichlorofluorescein diacetate

2',7'-Dichlorofluorescein diacetate
T20684-1mg	TargetMol Chemicals	1mg	Ask for price
Description: 2',7'-Dichlorofluorescein diacetate

2',7'-Dichlorofluorescein diacetate
T20684-50mg	TargetMol Chemicals	50mg	Ask for price
Description: 2',7'-Dichlorofluorescein diacetate

2',7'-Dichlorofluorescein diacetate
T20684-5mg	TargetMol Chemicals	5mg	Ask for price
Description: 2',7'-Dichlorofluorescein diacetate

2’,7’-Dichlorofluorescein, Hi-AR™
RM349-10G	EWC Diagnostics	1 unit	EUR 11.91
Description: 2’,7’-Dichlorofluorescein, Hi-AR™

5-(&6)-Carboxy-2', 7'-Dichlorofluorescein
51015-1	Biotium	EA	EUR 136

5-(&6)-Carboxy-2', 7'-Dichlorofluorescein
51016-1	Biotium	EA	EUR 148

5(6)-Carboxy-2',7'-dichlorofluorescein
C177958	Toronto Research Chemicals	1g	EUR 800
Description: 111843-78-8

6-Carboxy-2'',7''-dichlorofluorescein DA
GW0085	Glentham Life Sciences	100mg	EUR 688.97

6-Carboxy-2'',7''-dichlorofluorescein DA
GW0085-100	Glentham Life Sciences	100	EUR 353.2

6-Carboxy-2'',7''-dichlorofluorescein DA
GW0085-250	Glentham Life Sciences	250	EUR 668.2

5-Carboxy-2'',7''-dichlorofluorescein DA
GW5240	Glentham Life Sciences	100mg	EUR 688.97

5-Carboxy-2'',7''-dichlorofluorescein DA
GW5240-100	Glentham Life Sciences	100	EUR 353.2

5-Carboxy-2'',7''-dichlorofluorescein DA
GW5240-250	Glentham Life Sciences	250	EUR 668.2

5-Carboxy-2', 7'-Dichlorofluorescein (Sin
51017-1	Biotium	EA	EUR 136

2,7-Dichlorofluorescein (DCF) extrapure AR, ACS, 90%
79126	Sisco Laboratories	5 Gms	EUR 4.11
Description: Part A

5(6)-Carboxy-2?,7?-dichlorofluorescein diacetate
MBS5798861-100mg	MyBiosource	100(mg	EUR 220

5(6)-Carboxy-2?,7?-dichlorofluorescein diacetate
MBS5798861-25mg	MyBiosource	25(mg	EUR 155

5(6)-Carboxy-2?,7?-dichlorofluorescein diacetate
MBS5798861-50mg	MyBiosource	50(mg	EUR 185

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
T38123-10mg	TargetMol Chemicals	10mg	Ask for price
Description: 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
T38123-1g	TargetMol Chemicals	1g	Ask for price
Description: 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
T38123-1mg	TargetMol Chemicals	1mg	Ask for price
Description: 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
T38123-50mg	TargetMol Chemicals	50mg	Ask for price
Description: 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
T38123-5mg	TargetMol Chemicals	5mg	Ask for price
Description: 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

2,7-Dichlorofluorescein Diacetate (DCFH) extrapure, 97%
85048	Sisco Laboratories	25 Mg	EUR 19.5
Description: Part B

5(6)-Carboxy-2’,7’-dichlorofluorescein 3’,6’-Diacetate
C177895	Toronto Research Chemicals	1g	EUR 1200
Description: 127770-45-0

5-(and-6)-Carboxy-2',7'-dichlorofluorescein *Mixed isomers*
E37F235-100-mg	EnoGene	100 mg	EUR 408
Description: pH fluorescence probe

5-(and-6)-Carboxy-2', 7'-dichlorofluorescein *Mixed isomers*
MBS8579984-100mg	MyBiosource	100mg	EUR 340

5-(and-6)-Carboxy-2', 7'-dichlorofluorescein *Mixed isomers*
MBS8579984-5x100mg	MyBiosource	5x100mg	EUR 1470

5-(and-6)-Carboxy-2',7'-dichlorofluorescein-*Mixed-isomers*
E37F235	EnoGene	100-mg	EUR 408.33
Description: pH-fluorescence-probe

CDCF [5-(and-6)-Carboxy-2',7'-dichlorofluorescein] *Mixed isomers*
235-100mg	AAT Bioquest	100 mg	EUR 109
Description: CDCF [5(6)-carboxy-2',7'-dichlorofluorescein] is the fluorescent product of 5(6)-carboxy-2',7'-dichlorodihydrofluorescein diacetate and 5(6)-carboxy-2',7'-dichlorofluorescein diacetate in cells.

5(6)-Carboxy-2',7'-Dichlorofluorescein Diacetate Succinimidyl Ester
C177910	Toronto Research Chemicals	250mg	EUR 1200
Description: 147265-60-9

6-Carboxy-2’,7’-dichlorofluorescein 3’,6’-Diacetate Succinimidyl Ester
C177890	Toronto Research Chemicals	250mg	EUR 1800
Description: 852299-81-1

CDCFDA [5-(and-6)-Carboxy-2',7'-dichlorofluorescein diacetate] *Mixed isomers*
22025-100mg	AAT Bioquest	100 mg	EUR 109
Description: It is widely recognized that fluorescent labeling of cells is an effective means to determine total cell numbers or how many viable cells exist in a sample.

CDCFDA [5-(and-6)-Carboxy-2',7'-dichlorofluorescein diacetate] *Mixed isomers*
E37F22025-100-mg	EnoGene	100 mg	EUR 398
Description: Cell staining. Cytoplasmic staining.

CDCFDA [5-(and-6)-Carboxy-2', 7'-dichlorofluorescein diacetate] *Mixed isomers*
MBS8579951-100mg	MyBiosource	100mg	EUR 380

CDCFDA [5-(and-6)-Carboxy-2', 7'-dichlorofluorescein diacetate] *Mixed isomers*
MBS8579951-5x100mg	MyBiosource	5x100mg	EUR 1645

CDCFDA-[5-(and-6)-Carboxy-2',7'-dichlorofluorescein-diacetate]-*Mixed-isomers*
E37F22025	EnoGene	100-mg	EUR 398.33
Description: Cell-staining.-Cytoplasmic-staining.

CDCFDA, SE [5-(and-6)-Carboxy-2',7'-dichlorofluorescein diacetate, succinimidyl ester] *Mixed isomers*
22026-25mg	AAT Bioquest	25 mg	EUR 109
Description: It is widely recognized that fluorescent labeling of cells is an effective means to determine total cell numbers or how many viable cells exist in a sample.

CDCFDA, SE [5-(and-6)-Carboxy-2',7'-dichlorofluorescein diacetate, succinimidyl ester] *Mixed isomers*
E37F22026-25-mg	EnoGene	25 mg	EUR 533
Description: Cell staining. Cytoplasmic staining.

CDCFDA, SE [5-(and-6)-Carboxy-2', 7'-dichlorofluorescein diacetate, succinimidyl ester] *Mixed isomers*
MBS8579952-25mg	MyBiosource	25mg	EUR 480

CDCFDA, SE [5-(and-6)-Carboxy-2', 7'-dichlorofluorescein diacetate, succinimidyl ester] *Mixed isomers*
MBS8579952-5x25mg	MyBiosource	5x25mg	EUR 2120

CDCFDA,-SE-[5-(and-6)-Carboxy-2',7'-dichlorofluorescein-diacetate,-succinimidyl-ester]-*Mixed-isomers*
E37F22026	EnoGene	25-mg	EUR 533.33
Description: Cell-staining.-Cytoplasmic-staining.

5-(AND-6)-CARBOXY-2', 7'-DICHLOROFLUORESC
90040-1	Biotium	EA	EUR 188

2',7'-Dichlorofluorescin diacetate
D15325	Pfaltz & Bauer	50MG	EUR 175.32
Description: CAS N° 4091-99-0

2'',7''-Dichlorofluorescin diacetate
GW2593	Glentham Life Sciences	50mg	EUR 355.95

2'',7''-Dichlorofluorescin diacetate
GW2593-1	Glentham Life Sciences	1	EUR 388.8

2'',7''-Dichlorofluorescin diacetate
GW2593-250	Glentham Life Sciences	250	EUR 178.4

2'',7''-Dichlorofluorescin diacetate
GW2593-50	Glentham Life Sciences	50	EUR 83.3

Melting point SMP20 - EACH
MEL2100	Scientific Laboratory Supplies	EACH	EUR 1780.65

AI9100 Melting Point Meter - EACH
MEL1000	Scientific Laboratory Supplies	EACH	EUR 2106

AI9200 Melting Point Meter - EACH
MEL1010	Scientific Laboratory Supplies	EACH	EUR 2502.9

Melting Point Tube 75x1.35mm - PK1000
HAE3151	Scientific Laboratory Supplies	PK1000	EUR 186.3

AgileMelt TM Melting Point Device
AMPD-300	Avans Biotechnology Corp	each	EUR 900

SMP11 Melting Point Apparatus - EACH
MEL2000	Scientific Laboratory Supplies	EACH	EUR 1085.4

Melting Point Apparatus SMP30 - EACH
MEL2102	Scientific Laboratory Supplies	EACH	EUR 2926.8

SMP10 Melting Point Apparatus - EACH
MEL2104	Scientific Laboratory Supplies	EACH	EUR 1324.35

SMP50 Automatic Melting point - EACH
MEL2108	Scientific Laboratory Supplies	EACH	EUR 8379.45

Melting Point Apparatus SMP30 IQOQ - EACH
MEL2102IQOQ	Scientific Laboratory Supplies	EACH	EUR 3222.55

Qual Set Melting Point Range 40C to 240C - 1G
AQSMP001	Scientific Laboratory Supplies	1G	EUR 174.79

Melting Point Apparatus Thiele 150mm x 25mm - EACH
7251150X25	Scientific Laboratory Supplies	EACH	EUR 10.8

2,5-Dichlorofluorene
D434445	Toronto Research Chemicals	10mg	EUR 69
Description: 934748-28-4

2,7-Dichlorofluorene
D434465	Toronto Research Chemicals	1g	EUR 132
Description: 7012-16-0

2,7-Dichlorofluorene
MBS6113380-25g	MyBiosource	2.5(g	EUR 485

2,7-Dichlorofluorene
MBS6113380-5x25g	MyBiosource	5x2.5g	EUR 2025

4,7-Dichloro-fluoren-9-one
D433945	Toronto Research Chemicals	10mg	EUR 282

Brass Cooling Plug for Analog Melting Point Apparatus - EACH
MEL2010	Scientific Laboratory Supplies	EACH	EUR 47.25

5-Oxiranyl-2,7-dichlorofluorene
MBS6093845-25mg	MyBiosource	25(mg	EUR 530

5-Oxiranyl-2,7-dichlorofluorene
MBS6093845-5x25mg	MyBiosource	5x25mg	EUR 2240

2,7-Dichlorofluorenyl Bromomethyl Ketone
D434480	Toronto Research Chemicals	100mg	EUR 190
Description: 53221-22-0

2,7-Dichlorofluorenyl Bromomethyl Ketone
MBS6040484-50mg	MyBiosource	50(mg	EUR 525

2,7-Dichlorofluorenyl Bromomethyl Ketone
MBS6040484-5x50mg	MyBiosource	5x50mg	EUR 2210

Melting Point Capilary Tubes 75mm x 1.3-1.4mm Diam Open Both Ends - PK1000
CAP5010	Scientific Laboratory Supplies	PK1000	EUR 121.5

(E,Z)-9-(4-Chlorophenyl)methylene-5-oxiranyl-2,7-dichlorofluorene
C379640	Toronto Research Chemicals	10mg	EUR 121
Description: 252990-29-7

(E,Z)-9-(4-Chlorophenyl)methylene-5-oxiranyl-2,7-dichlorofluorene
MBS6077808-10mg	MyBiosource	10(mg	EUR 525

(E,Z)-9-(4-Chlorophenyl)methylene-5-oxiranyl-2,7-dichlorofluorene
MBS6077808-5x10mg	MyBiosource	5x10mg	EUR 2210

3,6-Dichlorofluoran
D15290	Pfaltz & Bauer	25G	EUR 217.25
Description: CAS N° 630-88-6

2,4-Dichlorofluorobenzene
D438810	Toronto Research Chemicals	2.5g	EUR 75
Description: 1435-48-9

3,4-Dichlorofluorobenzene 98%
D15330	Pfaltz & Bauer	20G	EUR 116.16
Description: CAS N° 1435-49-0

Dichlorofluoromethane - 1ML
S-1405	Scientific Laboratory Supplies	1ML	EUR 95.85

2,4-dichloro-6-fluorophenol
D400715	Toronto Research Chemicals	250mg	EUR 800
Description: 344-21-8

2,6-Dichloro-3-fluorophenol
D580255	Toronto Research Chemicals	500mg	EUR 3000
Description: 1803854-58-1

3,4-Dichloro-2-fluoroaniline
D434780	Toronto Research Chemicals	100mg	EUR 63
Description: 42965-55-9

Ethyl Dichlorofluoroacetate
E915895	Toronto Research Chemicals	1g	EUR 126
Description: 383-61-9

2,6-Dichloro-3-Fluoropyridine
20-abx188187	Abbexa	Ask for price Ask for price	25 g 100 g

3,5-Dichloro-4-fluoropyridine
20-abx180388	Abbexa	Ask for price Ask for price	1 g 5 g

2,3-Dichloro-5-fluoropyridine
D434395	Toronto Research Chemicals	1g	EUR 98
Description: 185985-40-4

3,5-Dichloro-2-fluorobenzoic Acid
D434470	Toronto Research Chemicals	5g	EUR 800
Description: 665022-07-1

2,4-Dichloro-5-fluoropyrimidine
20-abx182986	Abbexa	Ask for price Ask for price Ask for price	1 g 25 g 100 g

4,6-Dichloro-5-fluoropyrimidine
20-abx185179	Abbexa	Ask for price Ask for price Ask for price	1 g 5 g 10 g

4,6-Dichloro-5-fluoropyrimidine
D437193	Toronto Research Chemicals	100mg	EUR 69
Description: 213265-83-9

2,4-Dichloro-5-fluoro benzoyl chloride
20-abx180996	Abbexa	Ask for price Ask for price Ask for price	5 g 10 g 25 g

11-Dichloro-1-fluoroethane (Freon 141) - 1ML
S-1480	Scientific Laboratory Supplies	1ML	EUR 68.85

Methyl 3,5-dichloro-2-fluorobenzoate
M295930	Toronto Research Chemicals	5g	EUR 1200
Description: 1522125-32-1

3,5-Dichloro-6-fluoro-2,4-pyridinediamine
D392460	Toronto Research Chemicals	100mg	EUR 1200
Description: 38875-71-7

2,6-Dichloro-4-fluorophenylboronic acid
D475213	Toronto Research Chemicals	1g	EUR 322
Description: 1451392-99-6

3,5-Dichloro-4-fluorobenzotrifluoride
D15335	Pfaltz & Bauer	1G	EUR 295.21
Description: CAS N° 77227-81-7

2,4-Dichloro-5-fluoro-6-methylpyrimidine
20-abx184995	Abbexa	Ask for price Ask for price	250 mg 1 g

2,4-Dichloro-5-fluoro-7h-pyrrolo[2,3-d]pyrimidine
20-abx181641	Abbexa	Ask for price Ask for price Ask for price	250 mg 1 g 5 g

1-(2,6-Dichloro-5-fluoro-4-pyrimidinyl)ethanone
D367060	Toronto Research Chemicals	2.5g	EUR 800
Description: 1289559-65-4

4,6-Dichloro-3-fluoro-1H-pyrazolo[3,4-d]pyrimidine
D434455	Toronto Research Chemicals	100mg	EUR 4500

2-((dichlorofluoromethyl)thio)isoindoline-1,3-dione
D393990	Toronto Research Chemicals	250mg	EUR 800
Description: 719-96-0

4-(1-Bromoethyl)-2,6-dichloro-5-fluoropyrimidine-d3
B590964	Toronto Research Chemicals	100mg	EUR 1800

2,4-Dichloro-6-fluoroquinoline-3-carbonitrile
D580260	Toronto Research Chemicals	1g	EUR 1200
Description: 881313-89-9

1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone
MBS5786531-10mg	MyBiosource	10mg	EUR 160

1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone
MBS5786531-25mg	MyBiosource	25mg	EUR 200

1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone
MBS5786531-50mg	MyBiosource	50(mg	EUR 250

1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone
MBS5786531-5mg	MyBiosource	5(mg	EUR 145

1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone
T9728-10mg	TargetMol Chemicals	10mg	Ask for price
Description: 1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone

1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone
T9728-1g	TargetMol Chemicals	1g	Ask for price
Description: 1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone

1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone
T9728-1mg	TargetMol Chemicals	1mg	Ask for price
Description: 1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone

1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone
T9728-50mg	TargetMol Chemicals	50mg	Ask for price
Description: 1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone

1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone
T9728-5mg	TargetMol Chemicals	5mg	Ask for price
Description: 1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone

4-Amino-3,5-dichloro-6-fluoropyridin-2-ol Potassium Salt
A805775	Toronto Research Chemicals	500mg	EUR 800
Description: 94133-73-0

4-Bromo-2,6-dichloro-5-fluoro-3-pyridinecarboxylic Acid
B699893	Toronto Research Chemicals	1g	EUR 1109
Description: 1526945-64-1

(R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
B678833	Toronto Research Chemicals	1g	EUR 69
Description: 877399-00-3

3-(2,6-Dichloro-5-fluoropyridin-3-yl)-3-oxopropanoic Acid Ethyl Ester
D434200	Toronto Research Chemicals	1g	EUR 58
Description: 96568-04-6

3-(2,6-Dichloro-5-fluoropyridin-3-yl)-3-oxopropanoic Acid Ethyl Ester
MBS6049293-10g	MyBiosource	10g	EUR 500

3-(2,6-Dichloro-5-fluoropyridin-3-yl)-3-oxopropanoic Acid Ethyl Ester
MBS6049293-1g	MyBiosource	1(g	EUR 390

3-(2,6-Dichloro-5-fluoropyridin-3-yl)-3-oxopropanoic Acid Ethyl Ester
MBS6049293-25g	MyBiosource	25g	EUR 680

3-(2,6-Dichloro-5-fluoropyridin-3-yl)-3-oxopropanoic Acid Ethyl Ester
MBS6049293-50g	MyBiosource	50g	EUR 925

3-(2,6-Dichloro-5-fluoropyridin-3-yl)-3-oxopropanoic Acid Ethyl Ester
MBS6049293-5x50g	MyBiosource	5x50g	EUR 4015

3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine
20-abx184572	Abbexa	Ask for price Ask for price	5 mg 25 mg

2,4-Dichlorofluobenzene
20-abx184541	Abbexa	Ask for price Ask for price	25 g 100 g

2-(4,5-Dichloro-2-fluorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
C611000	Toronto Research Chemicals	25mg	EUR 3000
Description: 153833-81-9

4-(5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-2-methylbenzamide
D422010	Toronto Research Chemicals	250mg	EUR 11200

(R)-tert-Butyl 4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
B242310	Toronto Research Chemicals	250mg	EUR 500
Description: 877399-51-4

4-((S)-5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((R)-2-ethyl-3-oxoisoxazolidin-4-yl)-2-methylbenzamide
D422015	Toronto Research Chemicals	250mg	EUR 17000
Description: 1309959-62-3

4-((S)-5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((R)-2-(ethyl-d5)-3-oxoisoxazolidin-4-yl)-2-methylbenzamide
D422019	Toronto Research Chemicals	50mg	EUR 17000

Low Melting Agarose
E0303-50	EURx	50g	EUR 138.43
Description: Recommended for convenient recovery of nucleic acids after electrophoresis

Agarose Low Melting
MBS635338-100g	MyBiosource	100g	EUR 610

Agarose Low Melting
MBS635338-250g	MyBiosource	250g	EUR 1150

Agarose Low Melting
MBS635338-25g	MyBiosource	25g	EUR 280

Agarose Low Melting
MBS635338-50g	MyBiosource	50g	EUR 435

Agarose Low Melting
MBS635338-5x250g	MyBiosource	5x250g	EUR 5020

Agarose, Low Melting
RM861-100G	EWC Diagnostics	1 unit	EUR 533.55
Description: Agarose, Low Melting

Agarose, Low Melting
RM861-10G	EWC Diagnostics	1 unit	EUR 57.22
Description: Agarose, Low Melting

Agarose, Low Melting
RM861-25G	EWC Diagnostics	1 unit	EUR 125.79
Description: Agarose, Low Melting

Agarose LM Low Melting
AXY1006	Scientific Laboratory Supplies	PK10	EUR 3480.06

Agarose, Low melting gel
AB0015	Bio Basic	10g	EUR 96.54

HiQTM Low Melting Agarose
A0223-002	GenDepot	25g	EUR 190

HiQTM Low Melting Agarose
A0223-010	GenDepot	100g	EUR 420

HyAgarose? LM Agarose, Low Melting, 100g
R9012LM-100g	ACTGene	each	EUR 452.4

HyAgarose? LM Agarose, Low Melting, 500g
R9012LM-500g	ACTGene	each	EUR 1821.6

Agarose LM Low Melting - PK10
AXY1004	Scientific Laboratory Supplies	PK10	EUR 12779.1

Agarose -LM(melting temperature ≦65℃)
01161-12	NACALAI TESQUE	25G	EUR 140

Agarose -LM(melting temperature ≦65℃)
01161-54	NACALAI TESQUE	100G	EUR 357

Agar, powder(melting temperature ~80℃)
01057-05	NACALAI TESQUE	500G	EUR 95.9

HyAgarose? LM Agarose, Low Melting, 10g
R9012LM-10g	ACTGene	each	EUR 120

HyAgarose? LM Agarose, Low Melting, 50g
R9012LM-50g	ACTGene	each	EUR 262.8

Agarose Low Melting for molecular biology
32417	Sisco Laboratories	5 Gms	EUR 22.5
Description: Part B

Tubes Melting Open One End 100mm - PK1000
MEL3004	Scientific Laboratory Supplies	PK1000	EUR 147.15

HyAgarose™ LM Agarose, Low Melting, 10g
R9012LM	ACTGene	10g	EUR 43.98

AGAROSE, LOW MELT POINT
IB70050	IBI Scientific	50GM	EUR 254.65

AGAROSE, LOW MELT POINT
IB70051	IBI Scientific	25GM	EUR 115.63

AGAROSE, LOW MELT POINT
IB70056	IBI Scientific	100GM	EUR 377.98

AGAROSE, LOW MELT POINT
IB70057	IBI Scientific	250GM	EUR 924.25

AGAROSE, LOW MELT POINT
IB70058	IBI Scientific	500GM	EUR 1768.48

AGAROSE, LOW MELT POINT
IB70059	IBI Scientific	1KG	EUR 3156.47

AGAROSE LM, LOW MELTING, MOLECULAR BIOLOGY GRADE, 100G/UNIT, 10 UNITS PER CASE (AL)
AGR-LM-1001	CORNING	1/pk	EUR 4484.4
Description: Bioscience Mol Bio; Agarose

AGAROSE LM, LOW MELTING, MOLECULAR BIOLOGY GRADE, 50G/UNIT, 10 UNITS PER CASE (AL)
AGR-LM-501	CORNING	1/pk	EUR 2490
Description: Bioscience Mol Bio; Agarose

Agarose: high melting temperature/medium resolution for all of your standard DNA applications 500 g - EACH
DD4905009	Scientific Laboratory Supplies	EACH	EUR 1391.85

2,5-Dichlorofuran
D270185	Toronto Research Chemicals	500mg	EUR 800
Description: 42587-83-7

3',4'-Dichloroformanilide
D434401	Toronto Research Chemicals	250mg	EUR 800
Description: 5470-15-5

2,6-Dichloroformanilide
D434400	Toronto Research Chemicals	10g	EUR 215
Description: 10113-35-6

3,5-Dichloro-4-formylbenzoic Acid
L474988	Toronto Research Chemicals	100mg	EUR 64
Description: 153203-80-6

Osteoporosis Real-TM Typing NEW RT PCR test with melting analysis for detection of 16 osteoporosis- related genes mutations
H944-48FRT	Sacace Biotechnologies	48	EUR 1674.24

2,5-Dichloro-4'-fluorobenzophenone
D434920	Toronto Research Chemicals	5g	EUR 800
Description: 270903-87-2

(2E)-4-Bromo-2,4-dichloro-3-formyl-2-butenoic Acid
B679460	Toronto Research Chemicals	25mg	EUR 11200
Description: 441304-66-1

2,6‐DICHLORO‐5‐FLUORO‐3‐CYANOPYRIDINE
904010	Survival Technologies	each	Ask for price

2,6‐DICHLORO‐5‐FLUORONICOTINIC ACID
904012	Survival Technologies	each	Ask for price

Dichloro Fluoro Triazolin-3-one
D439950	Toronto Research Chemicals	50mg	EUR 7600

2,6‐DICHLORO‐5‐FLUORONICOTINAMIDE
904011	Survival Technologies	each	Ask for price

Ethyl 4,6-Dichloro-3-formyl-2-indolecarboxylate
E915910	Toronto Research Chemicals	2.5g	EUR 1200
Description: 153435-96-2

2,2-Dichloro-1-(4-fluorophenyl)-2-phenylethanone
D671165	Toronto Research Chemicals	1g	EUR 800
Description: 1403667-07-1